GW26-e1231 Preparation and Evaluation of SDF-1-targeted Ultrasound Contrast Agent
نویسندگان
چکیده
منابع مشابه
Effects of ultrasound and ultrasound contrast agent on vascular tissue
BACKGROUND Ultrasound (US) imaging can be enhanced using gas-filled microbubble contrast agents. Strong echo signals are induced at the tissue-gas interface following microbubble collapse. Applications include assessment of ventricular function and virtual histology. AIM While ultrasound and US contrast agents are widely used, their impact on the physiological response of vascular tissue to v...
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Conventional methods used to image and quantify microdamage in bone tissue are limited to thin histological sections. Therefore recent studies have begun to investigate methods for non-destructive, three-dimensional (3-D) detection and imaging of microdamage in bone tissue. The objective of this study was to investigate gold nanoparticles (Au NPs) as a potential damage-specific X-ray contrast a...
متن کاملCollapse Dynamics of Ultrasound Contrast Agent
Ultrasound contrast agents (UCAs) are micron-sized gas bubbles encapsulated with thin shells on the order of nanometers thick. The damping effects of these viscoelastic coatings are widely known to significantly alter the bubble dynamics for linear and low-amplitude behavior; however, their effects on strongly nonlinear and destruction responses are much less studied. This dissertation examines...
متن کاملUltrasound-induced Coalescence of Contrast Agent Microbubbles
ULTRASOUND-INDUCED COALESCENCE OF CONTRAST AGENT MICROBUBBLES M. POSTEMA*1,2, C. T. LANCÉE1, N. DE JONG1,3, P. MARMOTTANT3, and S. HILGENFELDT3, 1Dept. of Experimental Echocardiography, Thoraxcentre, Erasmus MC, 2Interuniversity Cardiology Institute of The Netherlands, 3Physics of Fluids, Dept. of Applied Physics, Faculty of Science and Technology, University of Twente. Corresponding e-mail: po...
متن کاملRGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo.
OBJECTIVE To prepare arginine-glycine-aspartate (RGD)-targeted ultrasound contrast microbubbles (MBs) and explore the feasibility of their use in assessing dynamic changes in αvβ3 integrin expression in a murine model of tumor angiogenesis. METHODS RGD peptides were conjugated to the surfaces of microbubbles via biotin-avidin linkage. Microbubbles bearing RADfK peptides were prepared as contr...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2015
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2015.06.985